|Title||Electron Microphotograph Slides|
.01 1714 tapered [collagen]
Each glass microphotograph slide has several views on it. Each is in a wax paper envelope with a handwritten number.
|Object Name||Plate, Microphotograph|
|Collection||William Banfield Collection|
|Caption||Electron Microphotograph Slides|
William G. Banfield was born in 1920, in Hartford, Connecticut. He earned his BS in genetics and agricultural chemistry at Rhode Island State College in 1943, and MD at Yale University School of Medicine in 1946. Banfield interned at Mt. Auburn Hospital, Cambridge, Massachusetts, and went on to serve as Captain, Medical Corps, at the Army Chemical Center, Maryland, until 1949. He then returned to Yale to work in the Department of Pathology under an American Cancer Society Fellowship until 1952, and later as Instructor in that department. In 1954, shortly after earning an Assistant Professorship at Yale, Dr. Banfield accepted the position in the Department of Pathology, National Cancer Institute. This Department was the diagnostic facility for the recently opened Clinical Center. He retired in 1980 and died in 2012. Banfield was also a pilot and scuba diver and raised sheep.
From "Dr. William Banfield Retires After 26 Years; Was Pioneer in Electron Microscopy," NIH Record, March 4, 1980, p. 4: "Trained in the then new field of electron microscopy at Yale University, he was the first with such skills in the NCI laboratory, and was one of the first scientists to obtain images of the polyoma virus, a tumor-causing agent in mice. As the research applications of the electron microscope progressed, Dr. Banfield was involved in refining the technology and developing a more versatile instrument, the scanning electron microscope. This machine is capable of producing three-dimensional images of objects ranging in size from cells to insects. In the last 10 years, Dr. Banfield has contributed to another innovation in electron microscope instrumentation, the electron probe. This device identifies small amounts of elements such as sodium, lead, and mercury in tissues and cells. It does so by creating a spectral picture of the X-ray wavelengths and energies of a specimen. Since each element has a characteristic spectral picture, identification is a matter of matching the pattern of the specimen with a known pattern. Dr. Banfield has used the probe to analyze elements associated with asbestos particles lodged in lung tissue, and to identify elements in nerves from a cancer patient who had been treated with an anticancer drug containing platinum. One of his recent projects has been to study the mineral changes that occur in skin connective tissue with age and after exposure to sunlight. The results may yield new knowledge about calcification, the deposition of calcium in healthy and diseased tissue, and about the nature of the fibers of connective tissue."
He also did work on viruses as a cause of cancer, particularly contagious tumors in hamsters, cow milker's nodule virus, the transmission of cancer through mosquito bites, and pike fish tumors. He worked with many important collaborators including Drs. Wallace Rowe, William Hagins, and Alan Rabson.
|Number of images||1|
NIH; NCI (National Cancer Institute)
NIH; NCI, Laboratory of Pathology
|Buildings||Building 10 ("CC" Warren Grant Magnuson Clinical Center)|
|NIH Property #||none|
|Old NIH Property #||none|